Bolton-Hunter reagent (sulpho-SHPP)

Supplier: G Bioscienes

Synonyms: 3-(4-Hydroxy-phenyl)-propionic acid-OSu, Water-Soluble Bolton-Hunter Reagent, Sulphosuccinimidyl-3 -(4-hydroxypheynyl) propionate

BC92
BC92EA 649 EUR
BC92
Bolton-Hunter reagent (sulpho-SHPP)
Bolton-Hunter reagent (sulpho-SHPP)

This sulpho-SHPP (water-soluble Bolton-Hunter Reagent) is designed to aid the labelling of proteins with radioactive iodine. Radioactive iodine (¹²⁵I) is routinely used by researchers to label proteins. The iodination of proteins can be performed enzymatically or chemically.


Bolton-Hunter Reagent is used to add tyrosine-like groups to end-terminal α-amino groups or ε-amino groups of lysine that result in increased protein iodination. The reaction is optimal at a pH of 8,5. This reagent is water soluble, and is ideal for proteins with masked or no tyrosine residues.


Formulation: Sulphosuccinimidyl-3-(4-hydroxyphenyl) propionate.

Formula: C₁₃H₁₃NO₅
MW: 263.249 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00005515
CAS Number: 34071-95-9
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