Anti-NANOG Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss
BS-10414R-CY5
BOSSBS-10414R-CY5EA 900 EUR
BOSSBS-10414R-CY5
Anti-NANOG Rabbit Polyclonal Antibody (Cy5®)
Antibodies
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]More Product Information
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