Anti-C1orf124 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss
BS-15013R-A488
BOSSBS-15013R-A488EA 893 EUR
BOSSBS-15013R-A488
Anti-C1orf124 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antibodies
Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading toMore Product Information
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SPECIFICATIONS

Environmentally Preferable
Antigen name C1orf124
Antigen synonyms Zinc finger RAD18 domain-containing protein C1orf124|DDDL1880|DVC1|DNA damage protein targeting VCP|CA124_HUMAN|RP5-876B10.3|SPRTN|SprT-like domain-containing protein Spartan|C1orf124|Chromosome 1 open reading frame 124|PRO4323|dJ876B10.3
Antibody type Primary
Clonality Polyclonal
Conjugation Alexa Fluor® 488
Reactivity
Host Rabbit
Gene ID 83932
Isotype IgG
ImmunoChemistry Yes
ImmunoFluorescence Yes
Modification Unmodified
Epitope 31-130/489
Immunogen KLH conjugated synthetic peptide derived from human C1orf124
Form Liquid
Molecular weight 55 kDa
Purification Purified by Protein A
Concentration 1 µg/µl
Storage buffer Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
Storage temperature Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Shipping temperature 4 °C
Tested applications ICC

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