Ac-IEPD-pNA

Supplier: ENZO LIFE SCIENCES

BMLP1330005
ENZOBMLP1330005EA 173 EUR
ENZOBMLP1330005
Ac-IEPD-pNA
Proteins and Peptides

Caspase substrate


Colorimetric granzyme B substrate. Combinatorial and kinetic studies have found the IEPD sequence to be optimal for cleavage of a tetrapeptide substrate by recombinant granzyme B, with a Km for Ac-IEPD-pNA of 57 µM. Cleavage of the substrate by granzyme B releases pNA, which can be detected by its absorbance at 405 nm.

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