Peptide A

Supplier: ENZO LIFE SCIENCES

BMLP3060500
ENZOBMLP3060500EA 227 EUR
ENZOBMLP3060500
Peptide A
Proteins and Peptides

Src kinase inhibitor


Sequence is pp60v-src (137-157), which is located in the SH3/SH2 domain region. Non-competitive inhibitor of Src and EGFR. Selectively inhibits protein tyrosine phosphorylation in cell extracts. Peptide is not phosphorylated by Src. IC50=7,5 µM for v-Src. Inhibitory target seems to be a catalytic negative regulatory domain of the tyrosine kinase.

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