Anti-IL2RA Mouse Monoclonal Antibody (CF568) [clone: IL2RA/423]

Supplier: Biotium
BNC680423-500 BNC680423-100
BNC680423-500EA 560 EUR
BNC680423-500 BNC680423-100
Anti-IL2RA Mouse Monoclonal Antibody (CF568) [clone: IL2RA/423]
Antibodies
Recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Type: Primary
Antigen: IL2RA
Clonality: Monoclonal
Clone: IL2RA/423
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
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