Anti-PTPRC Mouse Monoclonal Antibody (CF594) [clone: PTPRC/818]

Supplier: Biotium
BNC940818-500 BNC940818-100
BNC940818-500EA 560 EUR
BNC940818-500 BNC940818-100
Anti-PTPRC Mouse Monoclonal Antibody (CF594) [clone: PTPRC/818]
Antibodies
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4 T-cells, 50% of peripheral CD8 T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4 or CD8 T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO ve) from B cell lymphomas (CD45RA ve).

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: PTPRC/818
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR