Anti-TRIM29 Mouse Monoclonal Antibody (CF405S) [clone: TRIM29/1042]

Supplier: Biotium
BNC041042-500 BNC041042-100
BNC041042-500EA 560 EUR
BNC041042-500 BNC041042-100
Anti-TRIM29 Mouse Monoclonal Antibody (CF405S) [clone: TRIM29/1042]
Antibodies
This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Type: Primary
Antigen: TRIM29
Clonality: Monoclonal
Clone: TRIM29/1042
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human
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