Anti-PTPRC Mouse Monoclonal Antibody (CF405S) [clone: PTPRC/1132]

Supplier: Biotium
BNC041132-500 BNC041132-100
BNC041132-500EA 560 EUR
BNC041132-500 BNC041132-100
Anti-PTPRC Mouse Monoclonal Antibody (CF405S) [clone: PTPRC/1132]
Antibodies
CD45R, also designated CD45 and PTPRC, is identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: PTPRC/1132
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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