Anti-EPX Mouse Monoclonal Antibody (CF405S) [clone: AHE-1]

Supplier: Biotium
BNC041231-500 BNC041231-100
BTIUBNC041231-500EA 560 EUR
BTIUBNC041231-500 BTIUBNC041231-100
Anti-EPX Mouse Monoclonal Antibody (CF405S) [clone: AHE-1]
Antibodies
Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).

Type: Primary
Antigen: EPX
Clonality: Monoclonal
Clone: AHE-1
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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