Anti-BDNF Mouse Monoclonal Antibody [clone: BS375]

Supplier: Biosensis
BSENM-1729-100EA 302 EUR
BSENM-1729-100
Anti-BDNF Mouse Monoclonal Antibody [clone: BS375]
Antibodies
Brain derived neurotrophic factor (BDNF) is synthesized as a precursor (proBDNF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proBDNF is synthesized in neurons and glia (eg., microglia), transported anterogradely and retrogradely and may be released in an activity dependent manner.

Flow Cytometry (2 ug/106 cells); Immunocytochemistry (1-2 ug/mL); Other applications not yet tested. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: BDNF
Clonality: Monoclonal
Clone: BS375
Conjugation: Unconjugated
Epitope: A synthetic peptide (C-NGPKAGSRGLTS, aa: 47-58) of human proBDNF protein has been used as the immunogen. The sequence is located on the pro-domain of the proBDNF full-length protein.
Host: Mouse
Isotype: IgG1, k-light chain
Reactivity: Human, mouse, rat
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