Anacardic acid ≥98%
Supplier: Cayman Chemical
Synonyms:
2-Hydroxy-6-pentadecylbenzoic acid
Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (PCAF) with IC50 values of 8,5 and 5 µm, respectively.
Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. At 25 µmol/l, anacardic acid suppresses NF-κB activation, inhibits IκB-α phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.
Formula:
C₂₂H₃₆O₃ MW: 348.5 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD07368254 CAS Number: 16611-84-0 |
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