Benzo[a]pyrene ≥96% (by HPLC), Sigma-Aldrich®
Supplier: Merck
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Danger
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Synonyms:
Benzo[def]chrysene, BaP
M-Clarity™ quality level = MQ200
Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer.
Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
Formula:
C₂₀H₁₂ MW: 252.32 g/mol Boiling Pt: 495 °C (1013 hPa) Melting Pt: 176…178 °C Density: 1.351 g/cm³ (20 °C) |
MDL Number:
MFCD00003602 CAS Number: 50-32-8 EINECS: 200-028-5 UN: 2811 ADR: 6.1,III Merck Index: 12,01134 |
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