Human amyloid-beta (1-40) peptide
Supplier: Cayman Chemical
Amyloid-β (1-40) peptide Aβ (1-40) is a 40-residue protein fragment of the C-terminal portion of the β-amyloid protein implicated in Alzheimer’s disease. Aβ (1-40) is more abundant, less neurotoxic, and does not form oligomers as easily as amyloid-β (1-42) peptide (Aβ (1-42).
- More abundant
- Less neurotoxic
- Does not form oligomers as easily as amyloid-β (1-42) peptide (Aβ (1-42)
In rat cortical cultures, Aβ (1-40) (3 µM) prevented neuronal cell death by inhibiting fibril formation when administered concurrently with Aβ (1-42) (5, 10, and 20 µM). In the same study, Aβ (1-40) prevented neuronal damage when injected into rat entorhinal cortex with Aβ (1-42) (both at 400 µM).
Upozornení: This product is not for human or veterinary use.
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