DSP (Dithiobis(succinimidyl propionate)), powder, Sigma-Aldrich®
Supplier: Merck
Synonyms:
DTSSP, 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester), DSP Crosslinker, Lomant’s reagent, 3,3'-Dithiodipropionic acid bis(N-succinimidyl Ester), Di(N-succinimidyl)-3,3'-dithiodipropionate, Sulfo-DSP, DTSP, 3,3'-Dithiodipropionic acid di(N-succinimidyl Ester)
M-Clarity™ quality level = MQ200
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
- The disulfide linkage is cleavable by mild reduction
Application
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.
Upozornení: Avoid use of reducing agents during coupling reactions.
Formula:
C₁₄H₁₆N₂O₈S₂ MW: 404.41 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00042045 CAS Number: 57757-57-0 |
Specification Test Results
assay | ≥97.0% (N) |
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