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(Z)-4-Hydroxytamoxifen ≥98%

Supplier: ENZO LIFE SCIENCES
Description: Tamoxifen metabolite

New Product

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(Z)-4-Hydroxytamoxifen 99%

Catalog Number: (469501000.)
Supplier: Thermo Scientific
Description: (Z)-4-Hydroxytamoxifen 99%
UOM: 1 * 100 mg

New Product


Product Image-ICNA0215673891

Tamoxifen, white powder

Supplier: MP Biomedicals
Description: Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

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(Z)-4-HYDROXYTAMOXIFEN 1 * 5 mg

Catalog Number: (ABCAAB141943-5)
Supplier: Abcam
Description: (Z)-4-HYDROXYTAMOXIFEN 1 * 5 mg
UOM: 1 * 5 mg
Product Image-STMC74052

(Z)-4-Hydroxytamoxifen 1 * 5 mg

Catalog Number: (STMC74052)
Supplier: STEMCELL Technologies
Description: (Z)-4-Hydroxytamoxifen 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-ABCAAB143637-10

(E)-4-HYDROXYTAMOXIFEN 1 * 10 mg

Catalog Number: (ABCAAB143637-10)
Supplier: Abcam
Description: (E)-4-HYDROXYTAMOXIFEN 1 * 10 mg
UOM: 1 * 10 mg
Product Image-STMC74056

(Z)-4-Hydroxytamoxifen 1 * 25 mg

Catalog Number: (STMC74056)
Supplier: STEMCELL Technologies
Description: (Z)-4-Hydroxytamoxifen 1 * 25 mg
UOM: 1 * 25 mg
Image Unavailable-ABCAAB141943-25

(Z)-4-HYDROXYTAMOXIFEN 1 * 25 mg

Catalog Number: (ABCAAB141943-25)
Supplier: Abcam
Description: (Z)-4-HYDROXYTAMOXIFEN 1 * 25 mg
UOM: 1 * 25 mg
Image Unavailable-ABCAAB143638-25

(E,Z)-4-HYDROXYTAMOXIFEN (17197F0KYM) 1 * 25 mg

Catalog Number: (ABCAAB143638-25)
Supplier: Abcam
Description: (E,Z)-4-HYDROXYTAMOXIFEN (17197F0KYM) 1 * 25 mg
UOM: 1 * 25 mg
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4-HYDROXYTAMOXIFEN 1 * 5 mg

Catalog Number: (SIALH7904-5MG)
Supplier: Merck
Description: 4-HYDROXYTAMOXIFEN 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-SIALH6278-10MG

4-HYDROXYTAMOXIFEN 1 * 10 mg

Catalog Number: (SIALH6278-10MG)
Supplier: Merck
Description: 4-HYDROXYTAMOXIFEN 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-SIALH6278-50MG

4-HYDROXYTAMOXIFEN 1 * 50 mg

Catalog Number: (SIALH6278-50MG)
Supplier: Merck
Description: 4-HYDROXYTAMOXIFEN 1 * 50 mg
UOM: 1 * 50 mg
Image Unavailable-ABCAAB143637-25

(E)-4-HYDROXYTAMOXIFEN 1 * 25 mg

Catalog Number: (ABCAAB143637-25)
Supplier: Abcam
Description: (E)-4-HYDROXYTAMOXIFEN 1 * 25 mg
UOM: 1 * 25 mg
Image Unavailable-ABCAAB143637-5

(E)-4-HYDROXYTAMOXIFEN 1 * 5 mg

Catalog Number: (ABCAAB143637-5)
Supplier: Abcam
Description: (E)-4-HYDROXYTAMOXIFEN 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-ABCAAB141943-10

(Z)-4-HYDROXYTAMOXIFEN 1 * 10 mg

Catalog Number: (ABCAAB141943-10)
Supplier: Abcam
Description: (Z)-4-HYDROXYTAMOXIFEN 1 * 10 mg
UOM: 1 * 10 mg
Product Image-STMC74054

(Z)-4-Hydroxytamoxifen 1 * 10 mg

Catalog Number: (STMC74054)
Supplier: STEMCELL Technologies
Description: (Z)-4-Hydroxytamoxifen 1 * 10 mg
UOM: 1 * 10 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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