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5-Phospho-D-ribose 1-diphosphate pentasodium salt, white powder

Supplier: MP Biomedicals
Description: 5-Phosphorylribose-1-pyrophosphate Sodium Salt Hydrate has been used in a study to assess the relationship between the muscarinic receptor cationic current and internal calcium in guinea-pig jejunal smooth muscle cells. It has also been used in a study to investigate inhibitors of the bacterial cell wall biosynthesis of the enzyme Mur D.

Image Unavailable-PRSI90-362

Recombinant NAPRTase B. Subtilis (from E. coli)

Catalog Number: (PRSI90-362)
Supplier: ProSci Inc.
Description: Nicotinate Phosphoribosyltransferase (NAPRTase) is involved in the biological processes of pyridine nucleotide biosynthesis and nicotinate nucleotide salvage and functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
UOM: 1 * 50 µG
Image Unavailable-PRSI90-363

Human recombinant NAPRTase (from E. coli)

Catalog Number: (PRSI90-363)
Supplier: ProSci Inc.
Description: Human nicotinate phosphoribosyltransferase (NAPRTase) is localised in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
UOM: 1 * 50 µG
Image Unavailable-50032.

FURA-2 pentasodium salt ≥95% (by HPLC) fluorescent indicator, for calcium determination

Catalog Number: (50032.)
Supplier: Biotium
Description: Fura-2, pentasodium salt is a ratiometric fluorescent dye that binds to free intracellular calcium. It is membrane-impermeant and may be loaded into cells via microinjection or scrape loading.
UOM: 1 * 1 mg
Image Unavailable-50042.

Indo-1 pentasodium salt ≥95% (by HPLC) fluorescent indicator, for calcium determination

Catalog Number: (50042.)
Supplier: Biotium
Description: Membrane-impermeant calcium indicator that can be loaded into cells via microinjection or scrape loading.
UOM: 1 * 1 mg
Image Unavailable-50012.

FLUO-3 pentasodium salt ≥95% (by HPLC) fluorescent indicator, for calcium determination

Catalog Number: (50012.)
Supplier: Biotium
Description: Fluo-3, pentasodium is membrane-impermeant, but can be loaded into cells via microinjection or scrape loading.
UOM: 1 * 1 mg
Product Image-ACRO407290010

Pentasodium diethylenetriaminepentaacetate 40% in aqueous solution tech.

Supplier: Thermo Fisher Scientific
Description: Appearance: Clear solution

MSDS

Product Image-AATB21026

FURA-2 pentasodium salt

Catalog Number: (AATB21026)
Supplier: AAT BIOQUEST
Description: Among the ratiometric calcium indicators, Fura-2 and Indo-1 are most commonly used.
UOM: 1 * 1 mg
Product Image-AATB21016

FLUO-3 pentasodium salt

Catalog Number: (AATB21016)
Supplier: AAT BIOQUEST
Description: Calcium measurement is critical for numerous biological investigations.
UOM: 1 * 1 mg
Product Image-PRSI36-169

Anti-POLY Mouse Monoclonal Antibody [clone: 10H]

Catalog Number: (PRSI36-169)
Supplier: ProSci Inc.
Description: Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair and is associated with the negatively charged polymer of adenosine 5'-diphosphate (ADP)-ribose (PAR). PAR is synthesized from nicotinamide adenine dinucleotide (NAD+) by the poly(ADP-ribose) polymerase protein family (PARPs), of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks. PARP-1 is selectively activated by DNA strand breaks to catalyze the addition of long branched chains of PAR to a variety of nuclear proteins, most notably PARP itself. The amount of PAR formed in living cells with DNA damage is commensurate with the extent of the damage. Under DNA damage conditions, PAR undergoes a rapid turnover, with a half-life in the range of minutes, as PAR is rapidly hydrolyzed and converted to free ADP-ribose by the enzyme poly(ADP-ribose)glycohydrolase (PARG). PAR regulates not only cell survival and cell-death programmes, but also an increasing number of other biological functions with which novel members of the PARP family have been associated. These include transcriptional regulation, cell division, intracellular trafficking, inflammation and energy metabolism.
UOM: 1 * 100 µG
Product Image-AATB21058

Fura-8™ pentasodium salt

Catalog Number: (AATB21058)
Supplier: AAT BIOQUEST
Description: Although Fura-2 has become the preferred excitation-ratioable calcium indicator of choice, it has certain limitations (e.g., lower sensitivity than single wavelength calcium indicators such as Fluo-8® and Cal-520®).
UOM: 1 * 1 mg
Product Image-AATB21044

Indo-1 pentasodium salt ratiometric calcium indicator

Catalog Number: (AATB21044)
Supplier: AAT BIOQUEST
Description: Calcium measurements are critical for numerous biological investigations.
UOM: 1 * 1 mg
Product Image-0160-20G

Adenosine 5'-diphosphate disodium salt (ADP disodium salt) dihydrate, Ultrapure

Supplier: VWR Chemicals
Description: Adenosine-5'- diphosphate, disodium salt. Involved in energy and nucleic acid metabolism.

MSDS

Image Unavailable-ENZOALX480001G005

Adenosine 5'-diphosphate disodium salt (ADP disodium salt)

Supplier: ENZO LIFE SCIENCES
Description: Adenosine 5'-diphosphate disodium salt (ADP disodium salt)

New Product

Product Image-ENZOALX480002G005

Adenosine-5'-diphosphate monopotassium salt ≥87%

Supplier: ENZO LIFE SCIENCES
Description: Adenosine-5'-diphosphate monopotassium salt ≥87%

New Product

Image Unavailable-APOSBISN0106-100MG

Chloroquine diphosphate salt

Supplier: Apollo Scientific
Description: Chloroquine Diphosphate is an inhibitor of autophagylysosome and Toll-like receptor TLR signalling also acting as an ATM acitivator its an antimalarial drug.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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