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Product Image-AATB570

3-Carboxy-6,8-difluoro-7-hydroxycoumarin ≥90% [equivalent to Pacific Blue succinimidyl ester]

Catalog Number: (AATB570)
Supplier: AAT BIOQUEST
Description: PacBlue succinimidyl ester is the same molecule to Pacific Blue™ succinimidyl ester (Pacific Blue™ is the trademark of ThermoFisher).
UOM: 1 * 5 mg
Product Image-PIER22360

SMCC (N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate), Pierce™

Catalog Number: (PIER22360)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
UOM: 1 * 50 mg

MSDS Certificates


Product Image-PA63101

CyDye™ Mono-Reactive Maleimide Fluorescent Dyes, Cytiva

Supplier: Cytiva
Description: CyDye™ Mono-Reactive Maleimide Fluorescent Dyes are intensely fluorescent and highly water soluble, providing significant advantages over other existing fluorophores.

Product Image-PIER22308

EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester), Pierce™

Catalog Number: (PIER22308)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce EMCS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).
UOM: 1 * 50 mg
Product Image-AATB113

5-Carboxyfluorescein-N-succinimidyl ester (5-FAM SE) ≥90%

Supplier: AAT BIOQUEST
Description: 5-FAM, SE is the amine-reactive succinimidyl ester of single isomer 5-FAM acid.

Product Image-PIER26168

LC-SDA (NHS-LC-Diazirine) (succinimidyl 6-(4,4′-azipentanamido)hexanoate), Pierce™

Catalog Number: (PIER26168)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce LC-SDA (NHS-LC-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 12.5Å spacer arm separates the two photoreactive groups.
UOM: 1 * 50 mg
Product Image-PIER26169

SDAD (NHS-SS-Diazirine) (succinimidyl 2-((4,4'-azipentanamido)ethyl)-1,3'-dithiopropionate), Pierce™

Catalog Number: (PIER26169)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce SDAD (NHS-SS-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 13.5Å spacer arm containing a cleavable disulfide bond separates the two photoreactive groups.
UOM: 1 * 50 mg
Image Unavailable-SIAL803642-50MG

LC-SPDP (Succinimidyl 6-[3-(2-pyridylthio)propionamidohexanoate) ≥95%, Sigma-Aldrich®

Catalog Number: (SIAL803642-50MG)
Supplier: Merck
Description: The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8. Other buffers can be used provided they do not contain primary amines (or thiols or disulfide reducing reagents – see discussion of the sulfhydryl reactivity). The rate of reaction and degradation by hydrolysis increases with increasing pH; for example, the half-life of the NHS ester is several hours at pH 7 and less than 10 minutes at pH 9. NHS-ester reagents like SPDP and LC-SPDP have limited aqueous solubility and must be dissolved in organic solvent before adding them to a reaction mixture. Sulfo-NHS-ester reagents like Sulfo-LC-SPDP are water-soluble and can be added directly to aqueous reaction mixtures.
UOM: 1 * 50 mg
Product Image-AATB202

6-Carboxy-2',4,4',5',7,7'-hexachlorofluorescein succinimidyl ester (6-HEX SE) single isomer ≥90%

Catalog Number: (AATB202)
Supplier: AAT BIOQUEST
Description: 6-HEX, SE is the amine-reactive succinimidyl ester of 6-HEX acid.
UOM: 1 * 5 mg
Product Image-PIER22113

Pierce™ PEGylated SMCC Crosslinkers, Heterobifunctional

Supplier: Thermo Fisher Scientific
Description: Cross linkers are used for the identification of near-neighbour protein relationships and ligand-receptor interactions. Homobifunctional, amine-reactive NHS esters or imidates, and heterobifunctional, amine-reactive, photoactivatable phenyl azides are the most commonly used crosslinkers for these applications.

Product Image-PIER22298

BMPS (3-Maleimidopropionic acid N-hydroxysuccinimide ester), Pierce™

Catalog Number: (PIER22298)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.9 Å).
UOM: 1 * 50 mg
Image Unavailable-SIAL21955-25MG

5(6)-Carboxytetramethylrhodamine succinimidyl ester [5(6)-TAMRA SE], BioReagent suitable for fluorescence, Sigma-Aldrich®

Catalog Number: (SIAL21955-25MG)
Supplier: Merck
Description: 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester (TMR-SE) is used as an amine coupling reagent to form 5(6)-carboxytetramethylrhodamine (TMR) derivatized compounds such as proteins and drugs.
UOM: 1 * 25 mg
Image Unavailable-PIER20593

DSG (Disuccinimidyl glutarate), Pierce™

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce DSG is a water-insoluble, homo-bifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker often used for conjugating radiolabeled ligands to cell-surface receptors. The NHS ester is the simplest and most commonly used reactive group for crosslinking and labeling proteins and peptides. NHS esters react with primary amines on the N-termini of peptides and the  amine of lysine residues, forming a stable, covalent amide bond and releasing the NHS group.

Image Unavailable-ROTH0249.2

Acridine orange (hemizinc salt)

Supplier: Roth Carl
Description: Acridine orange (hemizinc salt)

Product Image-PIER26174

, Pierce™

Catalog Number: (PIER26174)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce Sulfo-LC-SDA (Sulfo-NHS-LC-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 12.5Å spacer arm separates the two photoreactive groups.
UOM: 1 * 50 mg
Product Image-AATB371

5(6)-Carboxytetramethylrhodamine succinimidyl ester [5(6)-TAMRA SE] ≥95%

Supplier: AAT BIOQUEST
Description: The succinimidyl esters of 5-TAMRA, 6-TAMRA or the mixed isomers are the primary labeling reagents for the preparation of orange fluorescent bioconjugates, including peptide, protein, nucleotide and nucleic acid conjugates, especially fluorescent antibodies and avidin derivatives used in immunochemistry.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
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