You Searched For: Bioss

Catalog Number: (BOSSBS-8217R-FITC)

Supplier: Bioss

Description: FAM59B

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11267R-A647)

Supplier: Bioss

Description: CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2). CCT2 is the β-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5); CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-7518R-FITC)

Supplier: Bioss

Description: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play role in redox homeostasis.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-15334R-CY3)

Supplier: Bioss

Description: C9orf61.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3565R-CY7)

Supplier: Bioss

Description: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3565R-HRP)

Supplier: Bioss

Description: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-7518R-A350)

Supplier: Bioss

Description: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play role in redox homeostasis.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-7518R-A647)

Supplier: Bioss

Description: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play role in redox homeostasis.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-7533R-CY7)

Supplier: Bioss

Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-12947R-A750)

Supplier: Bioss

Description: CRP2BP is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously expressed nuclear protein, with highest expression in skeletal muscle and heart.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-13377R-HRP)

Supplier: Bioss

Description: There are three different isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-13377R-CY7)

Supplier: Bioss

Description: There are three different isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5825R-A555)

Supplier: Bioss

Description: The PCDHA12 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five, which demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins which may play a role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-13377R-A647)

Supplier: Bioss

Description: There are three different isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-0423R-HRP)

Supplier: Bioss

Description: Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50% of gliomas.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-2060R-HRP)

Supplier: Bioss

Description: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.

UOM: 1 * 100 µl

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