You Searched For: Guanosine+5\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'-triphosphate+disodium

Catalog Number: (BOSSBS-8874R-FITC)

Supplier: Bioss

Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-8874R-A350)

Supplier: Bioss

Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-8874R-A488)

Supplier: Bioss

Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-8874R-A555)

Supplier: Bioss

Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-8874R-A647)

Supplier: Bioss

Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.

UOM: 1 * 100 µl

Sale

Supplier: Merck

Description: Guanosine 5'-triphosphate trisodium salt hydrate, Sigma-Aldrich®

Catalog Number: (USBI035096)

Supplier: US Biological

Description: Anti-ENTPD5 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Sale

Supplier: Merck

Description: Guanosine 5'-triphosphate trisodium salt hydrate, Sigma-Aldrich®

Supplier: Apollo Scientific

Description: Cytidine-5'-triphosphoric acid disodium salt (CTP-Na2)

New Product

Supplier: MP Biomedicals

Description: Soluble in water (50 mg/ml - clear solution).

Catalog Number: (MOLE78355753-100MG)

Supplier: Molekula

Description: Guanosine-5'-diphosphate disodium salt

UOM: 1 * 100 mg

Sale

Catalog Number: (EHERC14057150)

Supplier: EHRENSTORFER

Description: Guanosine-5'-monophosphate disodium salt

UOM: 1 * 0,1 g

Sale

Supplier: Merck

Description: Guanosine-5'-diphosphate disodium salt, Sigma-Aldrich®

Supplier: MP Biomedicals

Description: Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of adeoxyribose ring it is known as deoxyguanosine.
Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.

Supplier: Cytiva

Description: Easy to use, time saving solutions for <i>in vitro</i> transcription or for reactions requiring rNTPs of high purity.

Catalog Number: (MOLE66211644-5G)

Supplier: Molekula

Description: Guanosine-5'-monophosphate disodium salt

UOM: 1 * 5 g

Sale