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Image Unavailable-BOSSBS-8874R-CY3

Anti-GPBAR1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-8874R-CY3)
Supplier: Bioss
Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-A555

Anti-GPBAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-8874R-A555)
Supplier: Bioss
Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-A647

Anti-GPBAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-8874R-A647)
Supplier: Bioss
Description: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Product Image-USBI035096

Anti-ENTPD5 Rabbit Polyclonal Antibody

Catalog Number: (USBI035096)
Supplier: US Biological
Description: Anti-ENTPD5 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl
Image Unavailable-40026.

5-Bromouridine-5′-triphosphate sodium salt (BrUTP ) 10 mM in TE buffer

Catalog Number: (40026.)
Supplier: Biotium
Description: BrUTP (5-Bromouridine-5′-triphosphate) can be enzymatically incorporated into RNA and detected with anti-BrdU antibodies.
UOM: 1 * 25 µl
Image Unavailable-40033.

Biotin-11-uridine-5'-triphosphate, tetralithium salt (Biotin-11-UTP) 10 mM in buffer (Tris-HCl, pH 7.5)

Catalog Number: (40033.)
Supplier: Biotium
Description: Biotin-11-UTP (biotin-11-uridine-5'-triphosphate, tetralithium salt) can be enzymatically incorporated into RNA. The number 11 is the number of atoms in the linker between biotin and UTP.
UOM: 1 * 25 µl
Image Unavailable-ICNA0210190705

Guanosine 97.0-103.0%, off-white powder

Supplier: MP Biomedicals
Description: Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of adeoxyribose ring it is known as deoxyguanosine.
Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.

Image Unavailable-40036.

Biotin-11-2′-deoxycytidine-5′-triphosphate, tetralithium salt (Biotin-11-dCTP) 1 mM in TE buffer (pH 7.5)

Catalog Number: (40036.)
Supplier: Biotium
Description: Biotin-11-dCTP (Biotin-11-2′-deoxycytidine-5′-triphosphate, tetralithium salt) can be enzymatically incorporated into DNA via nick translation, random priming, or 3′-end terminal labeling. The number 11 is the number of atoms in the linker between biotin and dCTP.
UOM: 1 * 50 µl
Image Unavailable-40035.

Biotin-11-CTP (Biotin-11-cytidine-5′-triphosphate, tetralithium salt) 10 mM in buffer (TRIS-HCl pH 7.5)

Catalog Number: (40035.)
Supplier: Biotium
Description: Biotin-11-CTP (Biotin-11-cytidine-5′-triphosphate, tetralithium salt) can be enzymatically incorporated into RNA. The number 11 is the number of atoms in the linker between biotin and CTP.
UOM: 1 * 25 µl
Image Unavailable-N5000-500MG

Naphthol AS-MX phosphate disodium salt, Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Naphthol AS-MX phosphate disodium salt,phosphatase substrate

Image Unavailable-B1375-1G

Bathophenanthrolinedisulphonic acid disodium salt hydrate ≥95%, Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Bathophenanthrolinedisulfonic acid disodium salt hydrate has been used to measure iron to determine the solubility of iron in the biological sample. It has been used as an iron chelator to grow plants without Fe-EDTA (ethylenediaminetetraacetic acid).

Product Image-160226G

EDTA disodium salt 0.01 mol/l (0.02 N) in aqueous solution, AVS TITRINORM volumetric solution

Catalog Number: (160226G)
Supplier: VWR Chemicals
Description: EDTA disodium salt 0.01 mol/l (0.02 N) in aqueous solution, AVS TITRINORM volumetric solution
UOM: 1 * 5 L

MSDS Certificates


Image Unavailable-E8886-25G

Erythrosin B disodium salt, Sigma-Aldrich®

Catalog Number: (E8886-25G)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Erythrosin B disodium salt, Sigma-Aldrich®
UOM: 1 * 25 g

Certificates


Image Unavailable-4870.

EDTA disodium salt concentrate for dilution to 0.01 mol in aqueous solution, DILUT-IT®, Laboratory Reagent, J.T.Baker®

Catalog Number: (4870.)
Supplier: Avantor
Description: EDTA disodium salt concentrate for dilution to 0.01 mol in aqueous solution, DILUT-IT®, Laboratory Reagent, J.T.Baker®
UOM: 1 * 60 mL

MSDS Certificates


Product Image-0160-20G

Adenosine 5'-diphosphate disodium salt (ADP disodium salt) dihydrate, Ultrapure

Supplier: VWR Chemicals
Description: Adenosine-5'- diphosphate, disodium salt. Involved in energy and nucleic acid metabolism.

MSDS

Image Unavailable-219916-5G

Hydroxy naphthol blue disodium salt ACS, Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Hydroxy naphthol blue disodium salt, ACS reagent.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
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Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
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