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Image Unavailable-BOSSBS-12545R-A750

Anti-ATM Ser794 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (BOSSBS-12545R-A750)
Supplier: Bioss
Description: ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionising irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
UOM: 1 * 100 µl
Product Image-611-4314

VWR®, Semi-Micro Balances with Ioniser, SM and SMG Series

Supplier: VWR Collection
Description: Semi-micro balances with resolution of 0,01 mg and a built-in ioniser, which ensures accurate sample preparation. Static charges accumulate in different samples that are routinely weighed in the laboratory. These static charges can build up and alter the weighing value. By blowing ions, the built-in ioniser neutralises static electricity and within seconds the sample is ready to be weighed. The balance calibration system automatically calibrates the balance when there is a temperature change or at a set period of time (factory settings), this ensures accurate measurements even if the user has not manually calibrated the balance. All models have a stainless steel top pan.

Image Unavailable-114367-25G

Bromocresol green sodium salt in ACS Reagent grade water ≥90% (by HPLC), Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Bromocresol Green (BCG), also known as bromcresol green, is a synthetic, anionic, triphenylmethane dye belonging to the phthalein and sulphonphthalein dyes group. It is commonly used as a pH indicator as it changes colour from yellow to blue-green at pH 3,8 to 5,4. The monosodium salt of bromocresol green is highly ionisable in water. The dye at a higher pH level produces a large and weakly lipophilic dianion.

Image Unavailable-BOSSBS-8571R-A680

Anti-Histone H2A.X Ubiquityl Lys119 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-8571R-A680)
Supplier: Bioss
Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionising radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM: 1 * 100 µl
Product Image-786-155

Detergent removal system, DetergentOUT™ GBS10

Supplier: G-Biosciences
Description: Detergents are essential for protein solubility during protein extraction and sample preparation, especially when working with hydrophobic proteins. The presence of high concentrations of detergents in protein samples can impair ELISA, IEF, protease digestion of proteins and suppress peptide ionisation when analysed by mass spectrometry.

Product Image-MILFSLSV025NB

Millex® PVDF Syringe Filter

Catalog Number: (MILFSLSV025NB)
Supplier: Merck
Description: Durapore® PVDF syringe filter.
UOM: 1 * 250 items
Image Unavailable-BOSSBS-6167R-A680

Anti-NET1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-6167R-A680)
Supplier: Bioss
Description: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionising radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8165R-A680

Anti-RB1CC1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-8165R-A680)
Supplier: Bioss
Description: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionising radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8165R-A750

Anti-RB1CC1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-8165R-A750)
Supplier: Bioss
Description: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionising radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8571R-A750

Anti-Histone H2A.X Ubiquityl Lys119 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-8571R-A750)
Supplier: Bioss
Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionising radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM: 1 * 100 µl
Product Image-HEWLG2421-60001

LC/MS calibrant mixes

Catalog Number: (HEWLG2421-60001)
Supplier: Agilent
Description: Organic Standard, Electrospray ionisation (ESI) tuning mix, 100 ml
UOM: 1 * 100 mL
Image Unavailable-VARI393173901

Accessories for GC/MS

Catalog Number: (VARI393173901)
Supplier: VARIAN
Description: Gate assembly, internal ionisation source
UOM: 1 * 1 items
Image Unavailable-BOSSBS-6167R-A750

Anti-NET1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-6167R-A750)
Supplier: Bioss
Description: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionising radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
UOM: 1 * 100 µl
Product Image-PRIOPC/WSC/010

Accessories for autoclaves, Priorclave compact

Catalog Number: (PRIOPC/WSC/010)
Supplier: Priorclave
Description: Autoclave, Water softening system- ionised resin column water softener
UOM: 1 * 1 items
Product Image-BEHRB00223499

Accessories for deionizers behropur®

Catalog Number: (BEHRB00223499)
Supplier: BEHR
Description: Deionisers, Conductivity meter for de-ionisers B5 and B10
UOM: 1 * 1 items
Image Unavailable-ICNA0215227205

alpha-Chymotrypsin, MP Biomedicals

Supplier: MP Biomedicals
Description: One unit will hydrolyse 1,0 µmole of N-benzoyl-L-tyrosine ethyl ester (BTEE) per minute at pH 7,8 and 25 °C in the presence of ionised calcium.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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