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Image Unavailable-SPCMS1736-2.5LTGL

Sulphuric acid 95.0-98.0% FCC

Catalog Number: (SPCMS1736-2.5LTGL)
Supplier: Spectrum Chemical
Description: Sulfuric Acid, FCC is considered a general purpose food additive and is used to directly control pH during the processing of food by discouraging the growth of bacteria and spoilage microbes. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
UOM: 1 * 2,5 L
Image Unavailable-SPCMA1167-2.5KG

Ammonium chloride ≥99.0%, granular FCC

Catalog Number: (SPCMA1167-2.5KG)
Supplier: Spectrum Chemical
Description: Ammonium Chloride, Granular, FCC is an ingredient in nutritive media for yeasts and many microorganisms. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
UOM: 1 * 2,5 kg
Image Unavailable-BOSSBS-15482R-A750

Anti-hHR23b Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (BOSSBS-15482R-A750)
Supplier: Bioss
Description: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15482R-CY5

Anti-hHR23b Rabbit Polyclonal Antibody (Cy5)

Catalog Number: (BOSSBS-15482R-CY5)
Supplier: Bioss
Description: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A750

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-6634R-A750)
Supplier: Bioss
Description: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-SPCMZ1077-50KGBL

Zinc D-gluconate ≥97.0% USP

Supplier: Spectrum Chemical
Description: ZINC GLUCONATE, USP is a zinc salt of gluconic acid can also be manufactured by fermenting glucose. It comes as a white powder and is used in cold treating lozenges and as one of the more effective ways of delivering zinc as a dietary supplement. Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Image Unavailable-SPCMSO104-2.5KG

Sodium acetate, anhydrous ≥99.0% USP

Supplier: Spectrum Chemical
Description: Sodium Acetate, Anhydrous, USP is used as an electrolyte replenisher in isosmotic solution for parenteral replacement of acute losses of extracellular fluid without disturbing normal electrolyte balance. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Image Unavailable-SPCMSI115-500GM

Silver nitrate ≥99.8%, crystals USP

Supplier: Spectrum Chemical
Description: Silver Nitrate, Crystal, USP is used as an antibiotic for indolent wounds, corn and callus removal and as a Gonorrheal ophthalmia neonatorum prophylaxis. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Image Unavailable-SPCMAM180-500MLGL

Ammonia solution

Supplier: Spectrum Chemical
Description: Strong Ammonia Solution, NF has many uses such as in topical pharmaceutical solutions destined for treating insect bites. All Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Image Unavailable-SPCMB1095-2.5KG

2,6-Di-tert-butyl-p-cresol ≥99.0%, granular FCC

Supplier: Spectrum Chemical
Description: BHT, Granular, FCC is used in small quantities as a food additive as an antioxidant. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Image Unavailable-SPCMVA130-12KG

Vanillin NF

Supplier: Spectrum Chemical
Description: Vanillin NF

Image Unavailable-SPCMSO193-500GM

Sodium pyruvate ≥99%, Reagent Grade

Catalog Number: (SPCMSO193-500GM)
Supplier: Spectrum Chemical
Description: Sodium Pyruvate, Reagent is most often added to the cell culture media as an extra source of energy. Sodium pyruvate also has a protective action against hydrogen peroxide. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.
UOM: 1 * 500 g
Image Unavailable-SPCMT1640-5KGBL

Tetrahexyldecyl ascorbate

Catalog Number: (SPCMT1640-5KGBL)
Supplier: Spectrum Chemical
Description: Tetrahexyldecyl ascorbate
UOM: 1 * 5 kg
Image Unavailable-SPCMSO167-125GM

Sodium fluoride ≥98.5%, powder USP, Ph. Eur., BP

Catalog Number: (SPCMSO167-125GM)
Supplier: Spectrum Chemical
Description: Sodium Fluoride, Powder, USP, EP, BP is used to prevent cavities making teeth stronger and more resistant to decay caused by acid and bacteria. Toothpaste being the preferred delivery method. All Spectrum Chemical USP, EP, BP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
UOM: 1 * 125 g
Image Unavailable-SPCMA1330-12KG

Antimony(III) oxide, Reagent Grade

Supplier: Spectrum Chemical
Description: Antimony Trioxide, Reagent is an inorganic compound and crucial as a commercial compound of antimony. It is an opacifying agent for glasses, ceramics and enamels. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.

Image Unavailable-SPCMME163-500GM

Methyl-4-hydroxybenzoate ≥98.0% NF

Supplier: Spectrum Chemical
Description: Methylparaben, NF is an excipient used as a preservative. Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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