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Supplier: ENZO LIFE SCIENCES
Description: Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.

Supplier: ENZO LIFE SCIENCES
Description: Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.

Catalog Number: (ORIGTA329131)
Supplier: OriGene
Description: Anti-TANK Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (ORIGTA306342)
Supplier: OriGene
Description: Anti-TANK Rabbit Polyclonal Antibody
UOM: 1 * 100 µG


Catalog Number: (BOSSBS-1355R-CY3)
Supplier: Bioss
Description: TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, this protein can block TRAF2 binding to LMP1, the Epstein Barr virus transforming protein, and inhibit LMP1-mediated NF kappa B activation.
UOM: 1 * 100 µl


Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

Supplier: ENZO LIFE SCIENCES
Description: PARP5a inhibitor

Catalog Number: (ENZOBMLCR1100025)
Supplier: ENZO LIFE SCIENCES
Description: Cannabinoid receptor agonist.
UOM: 1 * 25 mg


Supplier: ENZO LIFE SCIENCES
Description: Inhibits α-mannosidase. Inhibits asparagine-linked oligosaccharide processing. Immunomodulator.

Supplier: ENZO LIFE SCIENCES
Description: Cytochrome P450 substrate.

Catalog Number: (ENZOBMLVR1040025)
Supplier: ENZO LIFE SCIENCES
Description: Activator of CB1 receptor and TRPV1
UOM: 1 * 25 mg


Catalog Number: (ENZOALX420036M025)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.
UOM: 1 * 25 mg


Supplier: ENZO LIFE SCIENCES
Description: Adenylate cyclase inhibitor

Catalog Number: (ENZOBMLGR3500025)
Supplier: ENZO LIFE SCIENCES
Description: HDAC inhibitor
UOM: 1 * 25 mg


Catalog Number: (ENZOBMLEI1980100)
Supplier: ENZO LIFE SCIENCES
Description: PKC inhibitor
UOM: 1 * 100 µG


Catalog Number: (ENZOBMLC1180001)
Supplier: ENZO LIFE SCIENCES
Description: Nicotinic acetylcholine receptor ligand.
UOM: 1 * 1 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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