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Image Unavailable-BOSSBS-1684R-A647

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1684R-A647)
Supplier: Bioss
Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0480R-CY7

Anti-IFNG Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0480R-CY7)
Supplier: Bioss
Description: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
UOM: 1 * 100 µl
Product Image-BOSSBS-2969R

Anti-HPV33 E7 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-2969R)
Supplier: Bioss
Description: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
UOM: 1 * 100 µl
Product Image-BOSSBS-0817R

Anti-MAGEA1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-0817R)
Supplier: Bioss
Description: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-AGLS200159

EletroTen-blue electroporation-competent cells

Catalog Number: (AGLS200159)
Supplier: AGILENT
Description: Achieve the highest transformation efficiencies available when cloning large plasmids and ligated DNA.
UOM: 1 * 5 items
Product Image-BOSSBS-6385R

Anti-Gas1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-6385R)
Supplier: Bioss
Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4778R-A350

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-4778R-A350)
Supplier: Bioss
Description: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4778R-A488

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-4778R-A488)
Supplier: Bioss
Description: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6817R-A488

Anti-MAGEA11 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-6817R-A488)
Supplier: Bioss
Description: Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3846R-A555

Anti-TGFB5/ TGFB1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-3846R-A555)
Supplier: Bioss
Description: Transforming Growth Factor beta 5 (TGF beta 5) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3846R-CY5.5

Anti-TGFB5/ TGFB1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-3846R-CY5.5)
Supplier: Bioss
Description: Transforming Growth Factor beta 5 (TGF beta 5) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4736R-CY5.5

Anti-HMMR Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-4736R-CY5.5)
Supplier: Bioss
Description: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6223R-CY5

Anti-BCAR1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6223R-CY5)
Supplier: Bioss
Description: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6223R-A680

Anti-BCAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-6223R-A680)
Supplier: Bioss
Description: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2763R-HRP

Anti-CRK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-2763R-HRP)
Supplier: Bioss
Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6223R-A555

Anti-BCAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-6223R-A555)
Supplier: Bioss
Description: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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