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Supplier: ENZO LIFE SCIENCES
Description: Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.

New Product

Supplier: ENZO LIFE SCIENCES
Description: Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.

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Supplier: ENZO LIFE SCIENCES
Description: Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.

New Product

Supplier: Cayman Chemical
Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC<sub>50</sub> = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.

Supplier: Saint Gobain Life Sciences
Description: Pure-Fit SIB eliminates entrapment and leak points that can occur with traditional assembly systems. The unique internal design eliminates voids or dead space that can lead to turbulence or stagnation of fluid flow creating the potential for bacterial growth.

Supplier: Saint Gobain Life Sciences
Description: Pure-Fit SIB eliminates entrapment and leak points that can occur with traditional assembly systems. The unique internal design eliminates voids or dead space that can lead to turbulence or stagnation of fluid flow creating the potential for bacterial growth.

Supplier: Apollo Scientific
Description: 2,8-Dichloroquinoline 98%

Supplier: Apollo Scientific
Description: 2,8-Quinolinediol

Catalog Number: (APOSOR309320-1G)
Supplier: Apollo Scientific
Description: 7-Bromo-2,8-dimethylquinoline
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: 4-Amino-2,8-dimethylquinoline

Supplier: Apollo Scientific
Description: 2,8-Dimethylquinoline hydrochloride

Supplier: Apollo Scientific
Description: 4-Chloro-2,8-dimethylquinoline

Supplier: Apollo Scientific
Description: 2,8-Dichlorocyclooctanone 95%

Catalog Number: (APOSOR911962-1G)
Supplier: Apollo Scientific
Description: 6-Chloro-2,8-dimethylquinoline 95%
UOM: 1 * 1 g


Catalog Number: (APOSOR307842-1G)
Supplier: Apollo Scientific
Description: 2,8-Dimethylquinolin-4(1H)-one
UOM: 1 * 1 g


Catalog Number: (APOSOR307991-1G)
Supplier: Apollo Scientific
Description: 5-Chloro-2,8-dimethylquinoline
UOM: 1 * 1 g


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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