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Anti-HSP90 Mouse Monoclonal Antibody (DyLight® 488)

Supplier: ENZO LIFE SCIENCES
Description: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

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Anti-S Mouse Monoclonal Antibody

Catalog Number: (ENZOALX804167C100)
Supplier: ENZO LIFE SCIENCES
Description: Host: Mouse, Isotype: IgM
UOM: 1 * 100 µG

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Anti-BAFF Rat Monoclonal Antibody (Biotin)

Catalog Number: (ENZOALX804157BC100)
Supplier: ENZO LIFE SCIENCES
Description: Host: Rat, Isotype: IgG1
UOM: 1 * 100 µG

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Anti-RANKL Mouse Monoclonal Antibody

Catalog Number: (ENZOALX804243C100)
Supplier: ENZO LIFE SCIENCES
Description: Host: Mouse, Isotype: IgG1 kappa
UOM: 1 * 100 µG

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TOFA ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Acetyl-CoA inhibitor

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SB202190 ≥98% (by TLC)

Catalog Number: (ENZOBMLEI2940001)
Supplier: ENZO LIFE SCIENCES
Description: Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis.
UOM: 1 * 1 mg

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PP2 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Src kinase inhibitor

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GW5074 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.

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17-AAG ≥98% (by TLC)

Catalog Number: (ENZOBMLEI3080001)
Supplier: ENZO LIFE SCIENCES
Description: HSP90 inhibitor
UOM: 1 * 1 mg

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Kenpaullone ≥98%

Catalog Number: (ENZOBMLEI3100005)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of CDK and GSK
UOM: 1 * 5 mg

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Product Image-ENZOALX804220R100

Anti-Poly(Adp-Ribose) Mouse Monoclonal Antibody

Catalog Number: (ENZOALX804220R100)
Supplier: ENZO LIFE SCIENCES
Description: Host: Mouse, Isotype: IgG3
UOM: 1 * 100 µl

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Anti-APRIL Mouse Monoclonal Antibody

Catalog Number: (ENZOALX804148C100)
Supplier: ENZO LIFE SCIENCES
Description: Host: Mouse, Isotype: IgG1
UOM: 1 * 100 µG

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Image Unavailable-ENZOBMLKI3400020

Proteasome assay buffer

Catalog Number: (ENZOBMLKI3400020)
Supplier: ENZO LIFE SCIENCES
Description: Assay buffer from the 20S Proteasome Assay Kit for Drug Discovery.
UOM: 1 * 20 mL

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Plates

Catalog Number: (ENZOBMLKI5840001)
Supplier: ENZO LIFE SCIENCES
Description: HTS Microplate
UOM: 1 * 1 SET

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(±)-Lisofylline ≥98%

Supplier: ENZO LIFE SCIENCES
Description: Potent inhibitor of phosphatidic acid generation

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Leukotriene D4 ≥98% (by HPLC)

Catalog Number: (ENZOBMLLD0040050)
Supplier: ENZO LIFE SCIENCES
Description: Prostanoid receptor ligand.
UOM: 1 * 50 µG

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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