You Searched For: STEMCELL Technologies

Supplier: STEMCELL Technologies

Description: Immunomagnetic isolation of untouched rat CD4+ T cells

Supplier: STEMCELL Technologies

Description: Immunodensity isolation of untouched B cells.

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, rhesus, sooty mangabey CD123 (IL-3Rα), PerCP-Cy5.5-conjugated.

Catalog Number: (STMC20144)

Supplier: STEMCELL Technologies

Description: EasySep™ buffer is recommended for EasySep™ cell separation protocols.

UOM: 1 * 1 L

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Supplier: STEMCELL Technologies

Description: Amine-labelling fluorescent dye for live/dead staining of mammalian cells - 100 tests.

Supplier: STEMCELL Technologies

Description: Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family. Noggin supports maintenance of undifferentiated human embryonic stem cells cultured in mouse embryonic fibroblast (MEF)-conditioned medium (Chaturvedi <i>et al.</i>), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba <i>et al.</i>). Noggin is essential for development of ectodermal structures including neural tube, tooth, hair follicle, and eye, as well as patterning of mesodermal somites and skeletal structures. It also influences chondrogenesis, osteogenesis, and joint formation (Krause <i>et al.</i>).

Catalog Number: (STMC100-0013)

Supplier: STEMCELL Technologies

Description: Differentiation kit for the generation of astrocyte precursors from human ES and iPS cell-derived neural progenitor cells.

UOM: 1 * 1 KIT

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Supplier: STEMCELL Technologies

Description: Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma <i>et al.</i>). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau <i>et al.</i>). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).

Catalog Number: (STMC79040)

Supplier: STEMCELL Technologies

Description: For purification of RNA from cells.

UOM: 1 * 1 KIT

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Catalog Number: (STMC75005)

Supplier: STEMCELL Technologies

Description: Resazurin (7-hydroxy-10-oxidophenoxazin-10-ium-3-one, sodium) is a blue fluorogenic dye used as a redox indicator in cell viability and proliferation assays for bacteria, yeast or mammalian cells.

UOM: 1 * 5 g

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Supplier: STEMCELL Technologies

Description: EasySep™ Red blood cell lysis buffer is for use as directed with EasySep™ or RoboSep™ whole blood kits for the lysis of red blood cells prior to separation from whole blood.

Catalog Number: (STMC100-0818)

Supplier: STEMCELL Technologies

Description: Fluorescent dye conjugates for staining cell membranes of gram-positive bacteria, mammalian cells, and yeast bud scars - 1000 µg.

UOM: 1 * 1.000 µG

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Supplier: STEMCELL Technologies

Description: The B18R protein, which is encoded by the B18R open reading frame in the Western Reserve (WR) strain of vaccinia virus, is a type I interferon (IFN)-binding protein that is known to inhibit IFN antiviral response (Colamonici <i>et al.</i>). B18R protein has been shown to exhibit neutralizing activity to type I interferon family members (Meyers <i>et al.</i>) and to protect cells from the antiviral effects of interferon (Vancová <i>et al.</i>). It was recently shown that HIV-1–dependent induction of type I IFN activity and BAFF protein levels was abrogated by the soluble B18R protein, with no effect observed on the cell viability (Gomez <i>et al.</i>). B18R protein has been reported to aid in cellular reprogramming using RNA-mediated gene delivery (Warren <i>et al.</i>; Yoshioka N <i>et al.</i>).

Catalog Number: (STMC100-1295)

Supplier: STEMCELL Technologies

Description: Lipocalin-2 (LCN2) is a member of the lipocalin superfamily, which share a highly conserved fold containing an eight-stranded antiparallel beta barrel (Flower), and transport small hydrophobic molecules. Playing a role in innate immunity, Lipocalin-2 acts as a potent bacteriostatic reagent by sequestering iron-containing siderophores (Flo <i>et al.</i>). It is mainly expressed in activated neutrophils, but is also secreted by other immune cells in response to infection. Lipocalin-2 has been implicated in multiple cellular processes, such as differentiation (Yang <i>et al.</i>), migration (Du <i>et al.</i>), and apoptosis (Devireddy <i>et al.</i>). <i>In vitro</i> studies suggest that lipocalin-2 is a potential therapeutic target for certain cancers, including colorectal cancer (CRC; Zhang <i>et al.</i>) and chronic lymphocytic leukemia (Bauvois <i>et al.</i>). This protein product contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, lipocalin-2 from STEMCELL comes lyophilised with ≥94% purity, and endotoxin levels are verified to be ≤1.0 EU/μg protein.

UOM: 1 * 100 µG

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Catalog Number: (STMC100-1297)

Supplier: STEMCELL Technologies

Description: A member of the pentraxin family of proteins, C-reactive protein (CRP) plays important roles in host defenses, including regulating complement activation in vivo (Sjoberg <i>et al.</i>), decreasing nitric oxide production, and inhibiting angiogenesis in vitro (Verma <i>et al.</i>, 2002). At specific concentrations, CRP directly inhibits endothelial progenitor cell (EPC) differentiation, survival, and function, and is thus implicated in the development of cardiovascular diseases (Verma <i>et al.</i>, 2004). CRP is primarily synthesized by liver hepatocytes, but also by other immune cells, such as macrophages and lymphocytes (Sproston and Ashworth). The expression of this acute-phase protein is induced by IL-6 and IL-1 secretion of macrophages and T-cells during inflammation. For consistency and reproducibility across your applications, C-reactive protein from STEMCELL comes lyophilised with ≥87% purity, and endotoxin levels are verified to be ≤1,0 EU/μg protein.

UOM: 1 * 200 µG

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Catalog Number: (STMC01992)

Supplier: STEMCELL Technologies

Description: For detection and measurement of human immunoglobulin A.

UOM: 1 * 1 KIT

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