You Searched For: Azbil Telstar Technologies

Catalog Number: (STMC60063PE.1)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human SSEA-5, PE-conjugated.

UOM: 1 * 25 Tests

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Catalog Number: (STMC60024AZ)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against mouse, rat, guinea pig CD90/CD90.1, APC-conjugated.

UOM: 1 * 100 µG

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Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2a antibody against mouse CD138 (syndecan-1), APC-conjugated.

Catalog Number: (STMC60143)

Supplier: STEMCELL Technologies

Description: Rabbit polyclonal antibody against human, mouse SHIP2, unconjugated.

UOM: 1 * 100 µl

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Catalog Number: (STMC60060BT)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgM antibody against human, mouse, rat SSEA-1 (CD15), biotin-conjugated.

UOM: 1 * 100 µG

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Catalog Number: (STMC60064)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgM antibody against human, rhesus, rabbit TRA­1­60 (podocalyxin), unconjugated.

UOM: 1 * 100 µG

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Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG2a antibody against human, chimpanzee, common marmoset CD45RO, APC-conjugated.

Catalog Number: (STMC60014)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, chimpanzee, horse CD38, unconjugated.

UOM: 1 * 100 µG

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Catalog Number: (STMC60007)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD2, unconjugated.

UOM: 1 * 100 µG

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Supplier: STEMCELL Technologies

Description: Transforming growth factor (TGF) beta 3 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes. TGF-beta 3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massagué; McDowell <i>et al.</i>). TGF-beta 3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall <i>et al.</i>; Holton <i>et al.</i>). TGF-beta 3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of fibroblast growth factors 2 and 18 (James <i>et al.</i>). This product is animal component-free.

New Product

Catalog Number: (STMC07915)

Supplier: STEMCELL Technologies

Description: Medium for dissociation of mouse spleen.

UOM: 1 * 10 Vial

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Supplier: STEMCELL Technologies

Description: Interleukin 1 alpha (IL-1α) is a member of the IL-1 family and a dual-function cytokine. Both the unprocessed precursor and a processed IL-1α protein signal through IL-1 receptor type 1 (IL-1R1). Various cells, including keratinocytes, thymic epithelium, hepatocytes, endothelial cells, fibroblasts, and the epithelial cells of mucous membranes, have high levels of intracellular IL-1α precursor. The precursor is also expressed on the surface of monocytes and B lymphocytes (Netea <i>et al.</i>). IL-1α recruits infiltrating cells to a site of injury during necrosis and plays an important role during processes of sterile inflammation (Cohen <i>et al.</i>; Rider <i>et al.</i>). During hypoxia, IL-1α contributes to angiogenesis (Carmi <i>et al.</i>). Studies in mice show that IL-1α is produced by microglia-like cells after ischemic brain injury, which contributes to the inflammation (Luheshi <i>et al.</i>).

Supplier: STEMCELL Technologies

Description: Hydrocortisone stock solution (200X) for use with PneumaCult™-ALI, MammoCult™, EpiCult™.

Catalog Number: (STMC05230)

Supplier: STEMCELL Technologies

Description: Functional assay kit to assess pluripotency by directed differentiation of human ES and iPS cells to all three germ layers.

UOM: 1 * 1 KIT

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Supplier: STEMCELL Technologies

Description: Stem cell factor (SCF) is an early-acting cytokine that plays a pivotal role in the regulation of embryonic and adult hematopoiesis. SCF promotes cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. Together with other cytokines such as thrombopoietin and Flt3/Flk-2 Ligand, SCF is commonly used to promote expansion of primitive hematopoietic stem cells and multi-potent progenitor cells in culture (Martin <i>et al.</i>; Kent <i>et al.</i>). In synergy with various growth factors, including IL-2, IL-3, IL-6, IL-7, G-CSF, and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy). SCF is also a primary growth and activation factor for mast cells and eosinophils. SCF exists in two biologically active splice forms: a soluble and a transmembrane isoform. Upon binding to its receptor (c-Kit tyrosine kinase receptor; CD117), it activates PI3K, JAK/STAT, and MAPK pathways. SCF and signaling from c-Kit have also been reported to play an important role in pigmentation, fertility, vasculogenesis, motility of the gut via c-Kit positive interstitial cells of Cajal, and in the migration of neuronal stem and progenitor cells to sites of injury in the brain. This product is animal component-free.

Supplier: STEMCELL Technologies

Description: Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf andamp; Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit <i>et al.</i>), the activation of metalloproteases that cleave VCAM-1 (Levesque <i>et al.</i>), and the release of norepinephrine from the sympathetic nervous system (Katayama <i>et al.</i>), leading to the release or mobilisation of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.