Anti-CTLA4 Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: UC10-4F10-11]

Supplier: Tonbo Biosciences
20-1522-U025 20-1522-U100
20-1522-U025EA 68.2 EUR
20-1522-U025 20-1522-U100
Anti-CTLA4 Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: UC10-4F10-11]
Antibodies
The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negativeMore Product Information
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SPECIFICATIONS

Antigen symbol CTLA4
Antigen name Cytotoxic T-lymphocyte-Associated Protein 4
Environmentally Preferable
Antigen synonyms IDDM12|GRD4|GSE|CD|CTLA-4|ALPS5|cytotoxic T-lymphocyte associated protein 4|CD152|CELIAC3
Antibody type Primary
Clonality Monoclonal
Conjugation APC (Allophycocyanin)
Clone UC10-4F10-11
Reactivity Mouse
Host Armenian hamster
Gene ID 12477
Isotype IgG1 kappa
Flow cytometry Yes
Cross adsorption none
Storage temperature Cool
Shipping temperature Ice

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