Anti-CD8A Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: 2.43]

Supplier: Tonbo Biosciences
20-1886-U100 20-1886-U025
20-1886-U100EA 178 EUR
20-1886-U100 20-1886-U025
Anti-CD8A Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: 2.43]
Antibodies
The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

Type: Primary
Antigen: CD8A (CD8a molecule)
Clonality: monoclonal
Clone: 2.43
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse
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