Anti-CD8A Rat Monoclonal Antibody (Peridinin Chlorophyll/Cy5.5®) [clone: 2.43]

Supplier: Tonbo Biosciences
65-1886-U100 65-1886-U025
65-1886-U100EA 226 EUR
65-1886-U100 65-1886-U025
Anti-CD8A Rat Monoclonal Antibody (Peridinin Chlorophyll/Cy5.5®) [clone: 2.43]
Antibodies
The 2.43 antibody reacts with the 32 to 34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation induced by binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck and facilitate intracellular signaling events that lead to T cell activation, development, andMore Product Information
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