Mouse Recombinant Shh

Supplier: STEMCELL Technologies

78066 78066.1 78066.2
STMC78066EA 421 EUR
STMC78066 STMC78066.1 STMC78066.2
Mouse Recombinant Shh
Proteins and Peptides

Sonic hedgehog (Shh) is a member of the Hedgehog family of secreted signaling proteins that has a prominent role in patterning during early mammalian development (Ho and Scott). It is expressed during early embryogenesis in a variety of tissues (Finco et al.). During patterning of the central nervous system, Shh directly acts on cells to specify neural cell fates, regulates proliferation and survival of oligodendrocyte precursors and neural crest cells and stimulates proliferation, differentiation, and axon growth (Ho and Scott; Martí). Shh also regulates T cell differentiation and activation (Crompton et al.). Recombinant Mouse Shh is a fully biologically active molecule.


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