Anti-CD19 Rat Monoclonal Antibody [clone: 6D5] (PE)

Supplier: STEMCELL Technologies
STMC60006PE.1EA 181 EUR
STMC60006PE.1 STMC60006PE
Anti-CD19 Rat Monoclonal Antibody [clone: 6D5] (PE)
Antibodies
Rat monoclonal IgG2a antibody against mouse CD19, PE-conjugated.

  • B cells

The 6D5 antibody reacts with CD19, an ~95 kDa type 1 transmembrane glycoprotein expressed on the surface of B cells throughout all stages of development, from early pre-B cells to plasma cells. Expression is down-regulated but persists in terminally differentiated plasma cells. CD19 is also found on follicular dendritic cells. By associating with CD21 and CD81, CD19 functions as a co-receptor for the B cell receptor and is involved in B cell activation and differentiation. Activation of CD19 is accompanied by phosphorylation of the cytoplasmic domain, which promotes binding to kinases and the induction of intracellular signaling cascades. Mutations in CD19 can result in severe immunodeficiency syndromes. Clone 6D5 recognizes the same epitope as clone ID3 in cross-competition assays. This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse B Cell Isolation Kit (Catalog #19854).

Upozornení: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD19
Clonality: Monoclonal
Clone: 6D5
Conjugation: PE
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Mouse
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