You Searched For: (±)-2-Pyrrolidinone-5-carboxylic+acid


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Catalog Number: (PRSI33-744)
Supplier: ProSci Inc.
Description: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.
UOM: 1 * 100 µG

New Product


Catalog Number: (PRSI33-768)
Supplier: ProSci Inc.
Description: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.
UOM: 1 * 100 µG

New Product


Catalog Number: (335495-5G)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Tris(4-nitrophenyl)amine, Technical Grade, Sigma-Aldrich®
UOM: 1 * 5 g


Catalog Number: (APOSOR310414-1G)
Supplier: Apollo Scientific
Description: N-Phenylquinolin-4-amine
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: 2-Methoxyquinolin-6-amine

Catalog Number: (APOSPC430591-500MG)
Supplier: Apollo Scientific
Description: 8-Fluoroquinazolin-2-amine
UOM: 1 * 500 mg


Catalog Number: (APOSOR309366-1G)
Supplier: Apollo Scientific
Description: 2-Methylquinolin-3-amine
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: Isoquinoline-5-amine

Supplier: Apollo Scientific
Description: 6-Phenoxypyridin-3-amine

Supplier: Apollo Scientific
Description: 3-Cyclopropylpyrazin-2-amine

Catalog Number: (APOSOR3549-1G)
Supplier: Apollo Scientific
Description: Isoquinoline-8-amine 98%
UOM: 1 * 1 g


Supplier: Apollo Scientific
Description: 4-Methoxypyrimidin-2-amine

Supplier: Thermo Fisher Scientific
Description: Isoquinoline-8-amine 97%
Supplier: Apollo Scientific
Description: Quinoxalin-2-amine 95%

Supplier: Apollo Scientific
Description: 5-Ethylpyrimidin-2-amine 95%

Supplier: Apollo Scientific
Description: 4-Phenoxybutan-1-amine 96%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
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