You Searched For: 5-Fluoropyrimidin-4-amine

Catalog Number: (MOLE22848333-100MG)

Supplier: Molekula

Description: 5-Fluorouridine

UOM: 1 * 100 mg

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Supplier: Merck

Description: 5-Fluorouridine, Sigma-Aldrich®

Catalog Number: (MOLE33980289-1G)

Supplier: Molekula

Description: 5-Fluorocytosine

UOM: 1 * 1 g

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Supplier: Merck

Description: 5-Fluoroorotic acid hydrate, Sigma-Aldrich®

Supplier: Merck

Description: 5-Fluoroorotic acid hydrate, Sigma-Aldrich®

Supplier: Thermo Fisher Scientific

Description: 5'-Deoxy-5-fluorocytidine 95%

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Catalog Number: (MOLE10130089-25MG)

Supplier: Molekula

Description: 5-Fluoro-5'-deoxyuridine (Doxifluridine)

UOM: 1 * 25 mg

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Supplier: MP Biomedicals

Description: 5-Fluorouracil (5-FU) inhibits the activity of thymidylate synthetase, which affects pyrimidine synthesis and leads to depletion of intracellular TTP pools.

Catalog Number: (MOLE59821456-100MG)

Supplier: Molekula

Description: 5-Fluoroorotic acid

UOM: 1 * 100 mg

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Catalog Number: (ROTH4015.3)

Supplier: Roth Carl

Description: 5-Fluoroorotic acid

UOM: 1 * 2,5 g

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Supplier: Merck

Description: 5-Fluoro-5'-deoxyuridine (Doxifluridine), Sigma-Aldrich®

Supplier: Thermo Fisher Scientific

Description: Thermo Scientific 5-Fluoroorotic Acid (5-fluorouracil-6-carboxylic acid monohydrate; 5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase

Catalog Number: (PRSI34-176)

Supplier: ProSci Inc.

Description: It recognises a protein of 36 kDa, identified as Thymidylate Synthase (TS). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

UOM: 1 * 100 µG

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Catalog Number: (PRSI33-918)

Supplier: ProSci Inc.

Description: Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

UOM: 1 * 100 µG

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Supplier: MP Biomedicals

Description: FOA is a derivative of a pyrimidine precursor and is selectively toxic to yeast cells which synthesize orotidine-5’-phosphate decarboxylase. FOA has been used in a positive selection for uracil-requiring mutants(in the presence of large numbers of wild-type cells) lacking OMPdecase or OPRTase activities. This results in efficient strains for effective transformation systems.

Catalog Number: (PRSI33-219)

Supplier: ProSci Inc.

Description: This antibody is specific for a protein of 36 kDa, identified as Thymidylate Synthase (TS). Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

UOM: 1 * 100 µG

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