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Image Unavailable-BOSSBS-4029R-FITC

Anti-CA9 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-4029R-FITC)
Supplier: Bioss
Description: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2495R-A555

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-2495R-A555)
Supplier: Bioss
Description: Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13115R-A555

Anti-ETV6 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-13115R-A555)
Supplier: Bioss
Description: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13115R-CY3

Anti-ETV6 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-13115R-CY3)
Supplier: Bioss
Description: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13115R-CY5

Anti-ETV6 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-13115R-CY5)
Supplier: Bioss
Description: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2763R-A750

Anti-Crk p38 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-2763R-A750)
Supplier: Bioss
Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2763R

Anti-CRK Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-2763R)
Supplier: Bioss
Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
UOM: 1 * 100 µl
Product Image-BOSSBS-6385R

Anti-Gas1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-6385R)
Supplier: Bioss
Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6136R-A488

Anti-AdV 5 E1A Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-6136R-A488)
Supplier: Bioss
Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
UOM: 1 * 100 µl
Image Unavailable-APOSBISN0074-50MG

BIBF-0775 97%

Catalog Number: (APOSBISN0074-50MG)
Supplier: Apollo Scientific
Description: BIBF0775 is an inhibitor of transforming growth factor β receptor I (TGFβRI) by soaking into the kinase domain of TGFβRI.
UOM: 1 * 50 mg
Image Unavailable-BOSSBS-6043R-HRP

Anti-NBL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6043R-HRP)
Supplier: Bioss
Description: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6043R-A647

Anti-NBL1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-6043R-A647)
Supplier: Bioss
Description: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
UOM: 1 * 100 µl
Image Unavailable-ELTN710801/40

ESD Safety Sandals, Joran Low S1PL

Supplier: ELTEN
Description: ESD safety shoe made from microfibre/textile upper and a rubber/TPU/EVA sole (Transformers).

Environmentally Preferable New Product

Image Unavailable-BOSSBS-1684R-CY5.5

Anti-SKI Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1684R-CY5.5)
Supplier: Bioss
Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1684R-A647

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1684R-A647)
Supplier: Bioss
Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6136R-CY5

Anti-AdV 5 E1A Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6136R-CY5)
Supplier: Bioss
Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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