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Image Unavailable-BOSSBS-11332R-FITC

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11332R-FITC)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11332R-A647

Anti-CNG channel beta 1/truncated GARP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11332R-A647)
Supplier: Bioss
Description: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl
Product Image-HACH2186400

Visual comparator test kit, ethylene glycol

Catalog Number: (HACH2186400)
Supplier: Hach
Description: Ethylene glycol (anti-freeze) contamination of automotive lubricants is an indication of a cracked engine block. Glycol presence also can indicate leaks in cooling systems. This test kit model EG-1 presents a purple colour if ethylene glycol and other 1,2 glycols are present in oil or water.
UOM: 1 * 1 KIT
Product Image-112-4322

Nitrile gloves, Microflex® 93-823

Catalog Number: (112-4322)
Supplier: Ansell
Description: These disposable nitrile gloves provide chemical and liquid protection. The most advanced glove in type I and IV allergy prevention, the Microflex 93-823 has been clinically proven to decrease redness and itchiness associated with contact dermatitis. Engineered without the use of chemical additives (including accelerators) that are known skin irritants, the 93-823 is safe for those with sensitive skin or prone to allergic reactions.
UOM: 1 * 100 items
Product Image-17-5498-51

Affinity chromatography columns, HiTrap™ MabSelect™ PrismA

Supplier: Cytiva
Description: These columns are prepacked with MabSelect™ PrismA protein A chromatographyn resin that has been improved with an optimised high-flow agarose base matrix and a genetically engineered protein A-derived ligand, allowing efficient cleaning between purification runs. These columns are suitable for purifying antibodies with affinity chromatography in research and process development.

Certificates

Image Unavailable-PROOVHGDSLFDBLK100

Reference materials, diesel fuel dilution Standards, VHG

Supplier: LGC Standards PROMOCHEM
Description: These standards are intended for use in the determination of fuel (diesel fuel or gasoline) in used engine oils by GC, IR, fuel dilution meter (fuel sniffer), or flash point analyser. They are prepared gravimetrically from well-characterised fuels and hydrocarbon oils, and are verified by GC-FID in accordance with ASTM Method D3524 or D3525.

Image Unavailable-BOSSBS-11715R-CY3

Anti-CLN8 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11715R-CY3)
Supplier: Bioss
Description: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11715R-FITC

Anti-CLN8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11715R-FITC)
Supplier: Bioss
Description: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11715R-CY5

Anti-CLN8 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11715R-CY5)
Supplier: Bioss
Description: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11715R-A680

Anti-CLN8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11715R-A680)
Supplier: Bioss
Description: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterised by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl
Image Unavailable-SIAL914800-500MG

Hyaluronic acid methacrylate, M.W. 170,000 - 250,000

Catalog Number: (SIAL914800-500MG)
Supplier: Merck
Description: Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid and N-acetyl-D-glucosamine found primarily in connective tissues. HA based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug deliery applications. The methacrylate functionalized hyaluronic acid is photo-crosslinkable, and can be used to generate crosslinked hydrogels.
UOM: 1 * 500 mg
Product Image-DISI2022-1024

Single-use bioreactor systems, BIOne

Supplier: DISTEK
Description: Distek, Inc. has developed a bench top scale single-use bioreactor (SUB) for mammalian cell growth, cell therapy, insect cells and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable head plate welded to a triple-layered liner that can be easily inserted into a non sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.

Image Unavailable-8170-02

J.T.Baker® BAKERBOND Speedisk® Aromatic Sulfonic Acid, SPE Columns

Supplier: Avantor
Description: Ultra-clean, PP columns with BAKERBOND® HPLC media are engineered to save time, minimise work and final solvent volumes and improve performance. Run times are up to nine times faster than conventional columns. The built-in column guard filter and higher analyte concentration may reduce or eliminate prefiltration and concentration steps.

Product Image-22002-5000K

DENARASE® High Salt

Supplier: C LECTA
Description: DENARASE High Salt is an engineered version of the wild-type<i> Serratia marcescens</i> endonuclease, which is commonly used for DNA removal applications in bioprocessing. Compared to the wild-type DENARASE, a few amino acids were substituted to provide the enzyme with an improved salt tolerance without losing its specificity for nucleic acids.

Image Unavailable-BOSSBS-11715R-A350

Anti-CLN8 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11715R-A350)
Supplier: Bioss
Description: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl
Product Image-7606-11

J.T.Baker® BAKERBOND Speedisk® C18, SPE Columns

Supplier: Avantor
Description: Ultra-clean, PP columns with BAKERBOND® HPLC media are engineered to save time, minimise work and final solvent volumes and improve performance. Run times are up to nine times faster than conventional columns. The built-in column guard filter and higher analyte concentration may reduce or eliminate pre-filtration and concentration steps.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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