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Leukotriene B4-dimethylamide ≥98% (by HPLC)

Catalog Number: (ENZOBMLEI1020050)
Supplier: ENZO LIFE SCIENCES
Description: Leukotriene B4 antagonist. Inhibits binding of [3H]-LTB4 to guinea pig lung membranes (Ki=0.13 µM). Antagonizes the degranulation response to LTB4 in rabbit PMNL (Kd=0.2 µM) acting, most likely, via receptor desensitization. Partial agonist at higher concentrations (5 µM).
UOM: 1 * 50 µG
Image Unavailable-ENZOBMLCR1110050

VDM-11 ≥98% (by TLC)

Catalog Number: (ENZOBMLCR1110050)
Supplier: ENZO LIFE SCIENCES
Description: Selective and potent inhibitor of the anandamide membrane transporter (AMT) (neuronal (C6 glioma cells): IC50=11µM; non-neuronal (rat RBL-2H3 cells): IC50=7.2µM) with negligible action at TRPV1 and weak action at CB1 receptor (CB1: Ki=5µM; CB2: Ki>5µM) and FAAH (IC50=3.7µM/ IC50>50µM (N18TG2 cell membranes).
UOM: 1 * 50 mg
Image Unavailable-ENZOBMLCN1350001

Rp-cAMPS ≥98% (by HPLC)

Catalog Number: (ENZOBMLCN1350001)
Supplier: ENZO LIFE SCIENCES
Description: Rp-cAMPS is a potent and specific competitive inhibitor of the activation of cAMP-dependent protein kinases by cAMP (IC50=4.9 µM) . Its cell permeability and complete resistance to cyclic nucleotide phosphodiesterases make it a unique tool for studying cAMP-dependent signaling. Significantly more lipophilc as compared to cAMP and thus membrane permeable in many biological systems. This product is not sterile.
UOM: 1 * 1 mg
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Human catestatin

Catalog Number: (ENZOBMLCP64200001)
Supplier: ENZO LIFE SCIENCES
Description: Human Chromogranin A [352-372]). Wild type catestatin, initially described as a potent catecholamine release inhibitory peptide. Cst located in the skin is active against Gram-negative and Gram-positive bacteria as well as against fungi and yeast. Also proposed as a modulator or regulator of cardiac function and as an anti-hypertensive agent.
UOM: 1 * 1 mg
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3-Morpholinosydnonimine ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: SIN-1 is a metabolite of molsidomine which decomposes spontaneously in solution in the presence of oxygen, releasing NO and superoxide anion under physiological conditions. Since NO and superoxide react to form peroxynitrite, SIN-1 may actually produce peroxynitrite under physiological conditions. It is a potent vasodilator and inhibitor of platelet aggregation and produces significant protective effects in myocardial ischemia-reperfusion. The effects of SIN-1 are markedly attenuated by nitroglycerin-induced tolerance. Inhibits cysteine proteases.

Image Unavailable-ENZOBMLCM1160005

Citrinin ≥98%

Supplier: ENZO LIFE SCIENCES
Description: MPTP activator

Image Unavailable-ENZOBMLCM1190025

CGP-37157 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Potent, selective inhibitor of mitochondrial Na+Ca2+ exchange. IC50=0.4µM. Blocks mitochondrial permeability transition.

Image Unavailable-ENZOBMLCM1110005

Oligomycin A ≥97% (by HPLC, TLC)

Catalog Number: (ENZOBMLCM1110005)
Supplier: ENZO LIFE SCIENCES
Description: Inhibits mitochondrial ATPases (F<sub>1</sub>F<sub>0</sub>). Stimulates lysosome acidification due to shunting of membrane potential. Induces apoptosis in a variety of cell types. Induces autophagy in the IPLB-LdFB insect cell line.
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLCM1230005

2-Methoxy-antimycin A ≥85%

Supplier: ENZO LIFE SCIENCES
Description: An analog of antimycin A (mixture of antimycin A1, A2, A3 and A4) which binds to the hydrophobic groove of Bcl-2 and Bcl-X<sub>L</sub> thereby inducing apoptosis. It displays selective cytotoxicity for Bcl-X<sub>L</sub>-expressing cells (10 µg/ml). Unlike antimycin A it does not exhibit general mitochondrial toxicity.

Image Unavailable-ENZOBMLCC2070005

Indirubin-3'-oxime ≥98%

Catalog Number: (ENZOBMLCC2070005)
Supplier: ENZO LIFE SCIENCES
Description: A potent inhibitor of glycogen synthase kinase-3β (IC50=22 nM). Also inhibits CDK1 (p34cdc2; IC50=180 nM) and CDK5 (IC50=100 nM). It reversibly arrests asynchronous HBL-100 cells at G2. Induces apoptosis in the mammary carcinoma cell line MCF-7 (10 µM).
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLCA4110025

BAPTA-AM ≥90% (by TLC)

Catalog Number: (ENZOBMLCA4110025)
Supplier: ENZO LIFE SCIENCES
Description: PKC activator
UOM: 1 * 25 mg
Image Unavailable-ENZOBMLCA4090050

Xestospongin C ≥90% (by TLC)

Catalog Number: (ENZOBMLCA4090050)
Supplier: ENZO LIFE SCIENCES
Description: Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca²⁺ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca²⁺ and K⁺ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized cells and not in cells with intact plasma membranes. Has vasodilatory properties.
UOM: 1 * 50 µG
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K-252a ≥98%

Supplier: ENZO LIFE SCIENCES
Description: Protein kinase inhibitor

Image Unavailable-ENZOBMLEI1900100

Tyrphostin 1 ≥99%

Supplier: ENZO LIFE SCIENCES
Description: An inactive tyrphostin, which may be used as a negative control.

Image Unavailable-ENZOBMLEI2060100

Auranofin ≥99%

Catalog Number: (ENZOBMLEI2060100)
Supplier: ENZO LIFE SCIENCES
Description: Anti-arthritic agent
UOM: 1 * 100 mg
Image Unavailable-ENZOBMLEI1630005

Meclofenamic acid sodium salt ≥98% (by HPLC)

Catalog Number: (ENZOBMLEI1630005)
Supplier: ENZO LIFE SCIENCES
Description: Dual 5-lipoxygenase (IC50=46.8 µM) and cyclooxygenase I and II inhibitor (IC50=0.6 µM). Clinically useful NSAID.
UOM: 1 * 5 g
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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