You Searched For: ProSci Inc.

Catalog Number: (PRSI27-865)

Supplier: ProSci Inc.

Description: TFAP4 acts in concert with AP-1 to activate SV40 late transcription in vitro.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI3509P)

Supplier: ProSci Inc.

Description: TSC2 peptide is used for blocking the activity of the TSC2 antibody.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI4633)

Supplier: ProSci Inc.

Description: SAPAP4 Antibody: SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI4645)

Supplier: ProSci Inc.

Description: Nanos2 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI2479)

Supplier: ProSci Inc.

Description: MCG10 Antibody: MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI25-561)

Supplier: ProSci Inc.

Description: ZNF625 may be involved in transcriptional regulation.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI4995P)

Supplier: ProSci Inc.

Description: IL-16 peptide is used for blocking the activity of IL-16 antibody.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-669)

Supplier: ProSci Inc.

Description: MSI2 contains two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-670)

Supplier: ProSci Inc.

Description: This protein mediates protein binding.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-652)

Supplier: ProSci Inc.

Description: The function remains unknown.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-653)

Supplier: ProSci Inc.

Description: TMEM63B belongs to the SPO75/TMEM63 family. It is a multi-pass membrane protein. The function of TMEM63B remains unknown.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI25-660)

Supplier: ProSci Inc.

Description: NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI5171P)

Supplier: ProSci Inc.

Description: RSPO1 peptide is used for blocking the activity of RSPO1 antibody.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI5587)

Supplier: ProSci Inc.

Description: CHORDC1 Antibody: The cysteine and histidine-rich domain (CHORD)-containing protein (CHORDC1) is a member of a highly conserved protein family that contains the plant protein RAR1 and the mammalian protein melusin. In mammals, CHORDC1 is an ADP-dependent HSP90-interacting protein, and this interaction is dependent on the ability of HSP90 to bind nucleotides. Recent experiments indicate that CHORDC1 mRNA is diurnally regulated in mouse hypothalamus, and that this regulation alters during development, suggesting that CHORDC1 may play a role in circadian mechanisms in the mammalian brain.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI5605)

Supplier: ProSci Inc.

Description: Lin28 Antibody: Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI5603)

Supplier: ProSci Inc.

Description: KLF4 Antibody: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.

UOM: 1 * 100 µG

Sale