You Searched For: ProSci Inc.

Catalog Number: (PRSI31-333)

Supplier: ProSci Inc.

Description: The exact functions of TPD52L3 remain unknown.

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI42-552)

Supplier: ProSci Inc.

Description: Anti-FRG1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI96-085)

Supplier: ProSci Inc.

Description: Recombinant CD80 (from HEK293 cells)

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI96-747)

Supplier: ProSci Inc.

Description: Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TRAILR1 / TNFRSF10A contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TRAILR-1 / DR4 / CD261 promotes the activation of NF-kappa-B.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI51-109)

Supplier: ProSci Inc.

Description: PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

UOM: 1 * 250 µl

Sale

Catalog Number: (PRSI96-722)

Supplier: ProSci Inc.

Description: T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3),which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM).

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI96-745)

Supplier: ProSci Inc.

Description: Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TRAILR1 / TNFRSF10A contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI96-718)

Supplier: ProSci Inc.

Description: TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFβR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-β1 / TGFB1 and TGF-β3 / TGFB3 with high affinity and TGF-β2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI96-719)

Supplier: ProSci Inc.

Description: Thrombospondin type-1 domain-containing protein 1 (THSD1) is also known as Transmembrane molecule with thrombospondin module (TMTSP), which is a single-pass type I membrane protein and contains a type 1 thrombospondin domain that is found in thrombospondin, a number of proteins involved in the complement pathway, as well as extracellular matrix proteins. In addition, THSD1 is widely expressed on endothelial cells, with highest expression in the lung. THSD1's ligand and function are unknown, but it is postulated that THSD1 may be involved in the regulation of vasculogenesis and/or angiogenesis through its interaction with its specific ligand.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI29-927)

Supplier: ProSci Inc.

Description: SLC43A3 belongs to the SLC43A transporter family and is a putative transporter.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI45-084)

Supplier: ProSci Inc.

Description: Anti-LEPR Goat Polyclonal Antibody

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI48-961)

Supplier: ProSci Inc.

Description: Anti-AQP2 Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

Sale

Catalog Number: (PRSI45-540)

Supplier: ProSci Inc.

Description: Anti-PTGER4 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI45-528)

Supplier: ProSci Inc.

Description: Anti-ELF5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSIXP-5197)

Supplier: ProSci Inc.

Description: Iterleukin 7 is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL-7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL-7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL-7 stimulates the proliferation of CD4+/CD8+ cells.

UOM: 1 * 100 µG

Sale

Catalog Number: (PRSI91-503)

Supplier: ProSci Inc.

Description: Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) is a cell membrane protein which belongs to the alkaline phosphatase family. There are at least four distinct but related alkaline phosphatases in humans: intestinal AP (IAP), placental AP(PLAP), germ cell AP (GCAP) and their genes are clustered on chromosome 2, tissue-nonspecific isozyme (TNAP) which gene is located on chromosome 1. Alkaline phosphatases (APs) are dimeric enzymes, it catalyse the hydrolysis of phosphomonoesters with release of inorganic phosphate. The native ALPL is a glycosylated homodimer attached to the membrane through a GPI-anchor. This isozyme may play a role in skeletal mineralisation. Mutations in ALPL gene have been linked directly to different forms of hypophosphatasia,characterised by poorly mineralised cartilage and bones, and this disorder can vary depending on the specific mutation since this determines age of onset and severity of symptoms.

UOM: 1 * 50 µG

Sale