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Catalog Number: (PRSI1607)

Supplier: ProSci Inc.

Description: Immunoblotting: 1/5000 - 1/50000, ELISA: 1/5000 - 1/50000, Immunohistochemistry: 1/100 - 1/1000

UOM: 1 * 0,05 mg

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Catalog Number: (PRSI55-424)

Supplier: ProSci Inc.

Description: 31472488

UOM: 1 * 400 µl

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Catalog Number: (PRSI29-115)

Supplier: ProSci Inc.

Description: MINA is a protein with a molecular weight of 53 kDa, which is localized in the nucleus and with part of the protein concentrated in the nucleolus. It is a direct target gene of Myc and is involved in mammalian cell proliferation.

UOM: 1 * 100 µG

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Catalog Number: (PRSI3453)

Supplier: ProSci Inc.

Description: Caspase-4 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1 beta and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.

UOM: 1 * 100 µG

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Catalog Number: (PRSI5021)

Supplier: ProSci Inc.

Description: TTBK2 Antibody: Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.

UOM: 1 * 100 µG

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Catalog Number: (PRSI5415P)

Supplier: ProSci Inc.

Description: IA-1 peptide is used for blocking the activity of IA-1 antibody.

UOM: 1 * 50 µG

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Catalog Number: (PRSI29-106)

Supplier: ProSci Inc.

Description: ZNF397 belongs to the krueppel C2H2-type zinc-finger protein family. This gene product, isoform 3, acts as a DNA-dependent transcriptional repressor.

UOM: 1 * 100 µG

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Catalog Number: (PRSI31-002)

Supplier: ProSci Inc.

Description: CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.

UOM: 1 * 100 µG

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Catalog Number: (PRSI6101)

Supplier: ProSci Inc.

Description: ZIP12 Antibody: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.

UOM: 1 * 100 µG

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Catalog Number: (PRSI6093)

Supplier: ProSci Inc.

Description: ZIP7 Antibody: The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.

UOM: 1 * 100 µG

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Catalog Number: (PRSI25-463)

Supplier: ProSci Inc.

Description: This protein belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 50 µG

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Catalog Number: (PRSI25-467)

Supplier: ProSci Inc.

Description: HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.

UOM: 1 * 50 µG

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Catalog Number: (PRSI25-483)

Supplier: ProSci Inc.

Description: TRIM33 is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined.

UOM: 1 * 50 µG

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Catalog Number: (PRSI2299P)

Supplier: ProSci Inc.

Description: DcR1 peptide is used for blocking the activity of DcR1 antibody.

UOM: 1 * 50 µG

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Catalog Number: (PRSI6541P)

Supplier: ProSci Inc.

Description: TGM7 peptide is used for blocking the activity of TGM7 antibody.

UOM: 1 * 50 µG

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Catalog Number: (PRSI6523P)

Supplier: ProSci Inc.

Description: ECRG2 peptide is used for blocking the activity of ECRG2 antibody.

UOM: 1 * 50 µG

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